ChemicalBook--->CAS DataBase List--->22594-69-0

22594-69-0

22594-69-0 Structure

22594-69-0 Structure
IdentificationBack Directory
[Name]

DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
[CAS]

22594-69-0
[Synonyms]

CORM-2
Dichlorotricarbonylruthenium dimer
Tetrachlorohexacarbonyldiruthenium
Tricarbonyldichlororuthenium dimer
TRICARBONYLDICHLORORUTHENIUM(II) DIMER
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
TRICARBONYLDICHLORORUTHENATE (II) DIMER
ruthenium(II) tricarbonyl chloride dimer
Dichlorotricarbonylruthenium(II) dimer,98%
Dichlorotricarbonylruthenium(II)dimer,min.98%
Dichlorotricarbonylruthenium(II) dimer, min. 98%
[Molecular Formula]

C6Cl4O6Ru2
[MDL Number]

MFCD00011528
[MOL File]

22594-69-0.mol
[Molecular Weight]

512.01
Chemical PropertiesBack Directory
[Appearance]

Off-white to slightly yellow powder
[Melting point ]

208°C (dec.)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[solubility ]

Soluble in DMSO
[form ]

crystal
[color ]

off-white
[Water Solubility ]

Insoluble in water
[InChIKey]

JYHHJVKGDCZCCL-UHFFFAOYSA-J
Hazard InformationBack Directory
[Chemical Properties]

Off-white to slightly yellow powder
[Uses]

Tricarbonyldichlororuthenium(II) dimer is used to enhance the coagulation and attenuation of vulnerability to fibrinolysis, modify thrombus growth or disintegration, enhances fibrinogen as a substrate for thrombin, and regulation of ion transport by gasotransmitters. Also used for various pharmacological studies. It is used as a CO donor for reactive oxygen species mediated bacterial killing.
[reaction suitability]

core: ruthenium
reagent type: catalyst
[in vivo]

Tricarbonyldichlororuthenium(II) dimer (1-10 mg/kg; oral gavage; single dose) has a protective effect in a rat model of gastric mucosal injury induced by ischemia-reperfusion[3].

Animal Model:Acute I/R gastric lesions treated male Wistar rats (250-300 g)[3]
Dosage:1, 5 or 10 mg/kg
Administration:Oral gavage (i.g.); single dose
Result:Significantly decreased the area of I/R gastric damage and significantly increased GBF at doses of 1 or 5 mg/kg.
Significantly increased mRNA expression of HMOX-1 but not HMOX-2 in gastric mucosa and significantly increased blood concentration at dose of 5 mg/kg.
Significantly increased gastric mucosal PGE2 content at dose of 5 mg/kg.
Significantly decreased mRNA expression of iNOS but not eNOS in gastric mucosa at dose of 5 mg/kg.
Significantly decreased 8-hydroxyguanozine (8-OHG) concentration in gastric mucosa at dose of 5 mg/kg.
Decreased the expression of pro- and anti-inflammatory markers' mRNA and proteins at dose of 5 mg/kg.
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22-36/37/38
[Safety Statements ]

26-37/39
[RIDADR ]

UN3466
[WGK Germany ]

3
[HazardClass ]

6.1
[PackingGroup ]

III
Spectrum DetailBack Directory
[Spectrum Detail]

DICHLOROTRICARBONYLRUTHENIUM (II) DIMER(22594-69-0)FT-IR
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