| | Identification | More |  | [Name] 
 (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
 |  | [CAS] 
 22677-21-0
 |  | [Synonyms] 
 2-PYRROLIDINONE, 4-HYDROXY-, (R)
 (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
 (R)-4-HYDROXY-2-PYRROLIDINONE
 (R)-4-HYDROXY-2-PYRROLIDONE
 (R)-BETA-HYDROXY-GAMMA-BUTYROLACTAM
 RHPD
 (R)-4-hydoroxyoyrolidone
 4-hydroxy-R-2-pyrrolidine
 (r)-(+)-β-hydroxy-γ-butyrolactam
 (r)-β-hydroxy-γ-butyrolactam
 2-Pyrrolidinone, 4-hydroxy-, (4R)-
 (R)+4-hydroxy-2-prrolidinone
 (4R)-4-Hydroxypyrrolidine-2-one
 (R)-4β-Hydroxypyrrolidine-2-one
 [4R,(-)]-4-Hydroxypyrrolidin-2-one
 (R)-4-hydroxy-2-pyrrolidione
 |  | [Molecular Formula] 
 C4H7NO2
 |  | [MDL Number] 
 MFCD00273364
 |  | [Molecular Weight] 
 101.1
 |  | [MOL File] 
 22677-21-0.mol
 | 
 | Chemical Properties | Back Directory |  | [Appearance] 
 white to light yellow crystal powde
 |  | [Melting point ] 
 156-160 °C
 |  | [Boiling point ] 
 363.6±35.0 °C(Predicted)
 |  | [density ] 
 1.292±0.06 g/cm3(Predicted)
 |  | [storage temp. ] 
 Sealed in dry,Room Temperature
 |  | [solubility ] 
 DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
 |  | [form ] 
 Powder
 |  | [pka] 
 13.62±0.20(Predicted)
 |  | [color ] 
 White to pale yellow
 |  | [Optical Rotation] 
 [α]23/D +43°, c = 1 in ethanol
 |  | [Water Solubility ] 
 Slightly soluble in water.
 |  | [BRN ] 
 1524193
 |  | [InChI] 
 InChI=1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m1/s1
 |  | [InChIKey] 
 IOGISYQVOGVIEU-GSVOUGTGSA-N
 |  | [SMILES] 
 N1C[C@H](O)CC1=O
 |  | [CAS DataBase Reference] 
 22677-21-0(CAS DataBase Reference)
 | 
 | Safety Data | Back Directory |  | [Hazard Codes ] 
 Xi
 |  | [Risk Statements ] 
 R36/37/38:Irritating to eyes, respiratory system and skin .
 R38:Irritating to the skin.
 R37:Irritating to the respiratory system.
 R36:Irritating to the eyes.
 |  | [Safety Statements ] 
 S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
 |  | [WGK Germany ] 
 3
 
 |  | [HS Code ] 
 29339900
 | 
 | Hazard Information | Back Directory |  | [Chemical Properties] 
 white to light yellow crystal powde
 |  | [Uses] 
 (R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.
 |  | [Uses] 
 The (R)-enantiomer intermediate in the preparation of Oxiracetam
 | 
 |  |