| Identification | More | [Name]
(S)-4-Hydroxy-2-pyrrolidinone | [CAS]
68108-18-9 | [Synonyms]
2-PYRROLIDINONE, 4-HYDROXY-, (4S)-
2-PYRROLIDINONE, 4-HYDROXY-, (S)
4-HYDROXY-PYRROLIDIN-2-ONE
(4S)-4-HYDROXYPYRROLIDIN-2-ONE
(S)-(-)-4-HYDROXY-2-PYRROLIDINONE
(S)-(+)-4-HYDROXY-2-PYRROLIDINONE
(S)-4-HYDROXY-2-PYRROLIDINONE
(S)-4-HYDROXY-2-PYRROLIDONE
(S)-4-HYDROXY-PYRROLIDINE-2-ONE
(S)-BETA-HYDROXY-GAMMA-BUTYROLACTAM
SHPD
(s)-(-)-β-hydroxy-γ-butyrolactam
(s)-β-hydroxy-γ-butyrolactam
(S)-4-Hydroxy-pyrrolidin-2-one | [Molecular Formula]
C4H7NO2 | [MDL Number]
MFCD00273370 | [Molecular Weight]
101.1 | [MOL File]
68108-18-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
156-159 °C (lit.) | [alpha ]
-41 º (c=% in ethanol) | [Boiling point ]
363.6±35.0 °C(Predicted) | [density ]
1.292±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [Water Solubility ]
Slightly soluble in water | [form ]
Solid | [pka]
13.62±0.20(Predicted) | [color ]
White to off-white | [Optical Rotation]
[α]23/D 43°, c = 1 in ethanol | [BRN ]
1524192 | [InChIKey]
IOGISYQVOGVIEU-VKHMYHEASA-N | [CAS DataBase Reference]
68108-18-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystal | [Uses]
(S)-(?)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:
- Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.
- Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.
| [Uses]
The (S)-enantiomer intermediate in the preparation of Oxiracetam | [General Description]
4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine. | [Synthesis]
10.1 g (100 mmol) of 2-oxiranylacetamide, CuI
0.95 g (5 mmol), cesium carbonate 2 g (200 mmol) was added to 150 ml of ammonia in a saturated solution of methanol, 55 ℃ for stirring reaction for 8 h, the reaction solution was concentrated under reduced pr |
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J & K SCIENTIFIC LTD.
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https://www.jkchemical.com |
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Energy Chemical
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www.energy-chemical.com |
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T&W GROUP
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