| Identification | Back Directory | [Name]
N,N-Diethanol amine-PEG4-Boc | [CAS]
2279944-66-8 | [Synonyms]
N,N-Diethanol amine-PEG4-Boc
N,N-diethanol amine-PEG4-tert-butyl ester | [Molecular Formula]
C19H39NO8 | [MDL Number]
MFCD31811482 | [MOL File]
2279944-66-8.mol | [Molecular Weight]
409.51 |
| Hazard Information | Back Directory | [Description]
N,N-diethanol amine-PEG4-tert-butyl ester is a PEG reagent with two hydroxyl moieties. The t-butyl group can be deprotected under acidic conditions. The hydrophilic PEG spacers increase the compounds water solubility in aqueous media. | [Uses]
N,N-Diethanol amine-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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