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2306193-99-5

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2306193-99-5 Structure

2306193-99-5 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2306193-99-5
[Synonyms]

VH 101, phenol
Phenolic VH101
E3 ligase Ligand 19
VH032-cyclopropane-F
(2S,4R)-1-((S)-2-(1-fluorocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
(2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
[Molecular Formula]

C26H33FN4O5S
[MDL Number]

MFCD32201089
[MOL File]

2306193-99-5.mol
[Molecular Weight]

532.63
Chemical PropertiesBack Directory
[Boiling point ]

841.7±65.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

9.12±0.35(Predicted)
[color ]

White to yellow
Hazard InformationBack Directory
[Uses]

VH032-cyclopropane-F (VH 101, phenol) is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal hydroxyl group. Allows rapid conjugation with many linkers containing active leaving groups. A basic building block for development of a protein degrader library.
[reaction suitability]

reagent type: ligand
[IC 50]

VHL
[storage]

Store at +4°C
Spectrum DetailBack Directory
[Spectrum Detail]

VH 101, phenol(2306193-99-5)1HNMR
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