| Identification | Back Directory | [Name]
VH 032 phenol-linker 1 | [CAS]
2376990-26-8 | [Synonyms]
VH 032 phenol-linker 1
VH 032 phenol-alkylC4-amine
(S,R,S)-AHPC-phenol-C4-NH2 (dihydrochloride) | [Molecular Formula]
C28H42ClN5O5S | [MOL File]
2376990-26-8.mol | [Molecular Weight]
596.18 |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-phenol-C4-NH2 (VH032-phenol-C4-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC?based VHL ligand and a linker used in?PROTAC?technology[1]. | [storage]
Store at -20°C | [References]
[1] Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery.?Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. DOI:10.1016/j.csbj.2019.01.006
[2] [3].Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277 |
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