| Identification | Back Directory | [Name]
SSD114 hydrochloride | [CAS]
2319790-02-6 | [Synonyms]
SSD114 HCl (SSD114 Hydrochloride) | [Molecular Formula]
C18H21ClF3N3O | [MDL Number]
MFCD31619246 | [MOL File]
2319790-02-6.mol | [Molecular Weight]
387.83 |
| Hazard Information | Back Directory | [Uses]
SSD114 hydrochloride is a novel GABAB receptor positive allosteric modulator. | [in vivo]
The onset of loss of righting reflex (LORR) is reduced by pretreatment with SSD114 hydrochloride [F(5,30)=4.55, P<0.005]. Post hoc analysis indicates that the onset of LORR is significantly lower in mouse groups pretreated with doses of SSD114 hydrochloride equal to or higher than 10 mg/kg than in vehicle-treated mice. The duration of LORR is increased by pretreatment with SSD114 hydrochloride [F(5,30)=4.81, P<0.005]. Post hoc analysis indicates that the duration of LORR is significantly longer in mouse groups pretreated with 10 and 100 mg/kg SSD114 hydrochloride than in vehicle-treated mice[1]. | [storage]
Store at -20°C | [References]
[1] Porcu A, et al. In vitro and in vivo pharmacological characterization of SSD114, a novel GABAB positive allosteric modulator. Eur J Pharmacol. 2016 Nov 15;791:115-123. DOI:10.1016/j.ejphar.2016.08.032 |
|
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|