| Identification | Back Directory | [Name]
VH 032-linker 7 | [CAS]
2341796-73-2 | [Synonyms]
VH 032-linker 7
VH 032 amide-alkylC2-amine
(S,R,S)-AHPC-C2-NH2 dihydrochloride
(2S,4R)-1-((S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
(2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride | [Molecular Formula]
C25H36ClN5O4S | [MOL File]
2341796-73-2.mol | [Molecular Weight]
538.1 |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1]. | [IC 50]
VHL | [storage]
Store at -20°C | [References]
[1] Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1. |
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