| Identification | Back Directory | [Name]
(S,R,S)-AHPC-C10-NH2 dihydrochloride | [CAS]
2341796-75-4 | [Synonyms]
VH 032-linker 10
VH 032 amide-alkylC10-amine
VH032-C10-NH2 dihydrochloride
S)-AHPC-C10-NH2 dihydrochloride
(S,R,S)-AHPC-C10-NH2 dihydrochloride
(2S,4R)-1-[(2S)-2-(11-aminoundecanoylamino)-3,3-dimethyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide | [Molecular Formula]
C33H52ClN5O4S | [MDL Number]
MFCD32705126 | [MOL File]
2341796-75-4.mol | [Molecular Weight]
650.32 |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-C10-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC[1]. | [IC 50]
VHL | [storage]
Store at -20°C | [References]
[1] Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31. DOI:10.1002/cmdc.201900497 |
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