ChemicalBook--->CAS DataBase List--->2341796-80-1

2341796-80-1

2341796-80-1 Structure

2341796-80-1 Structure
IdentificationBack Directory
[Name]

VH 032-linker 11
[CAS]

2341796-80-1
[Synonyms]

VH 032-linker 11
VH 032 amide-alkylC8-amine
[Molecular Formula]

C31H48ClN5O4S
[MOL File]

2341796-80-1.mol
[Molecular Weight]

622.27
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Uses]

(S,R,S)-AHPC-C8-NH2 dihydrochloride (VH032-C8-NH2 dihydrochloride) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for?AKT?PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1].
[IC 50]

VHL
[storage]

Store at -20°C
[References]

[1] [1].Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.
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