| Hazard Information | Back Directory | [Description]
N’-Boc-N-(Gly-Oleoyl)-Lys is a lipid modified peptide linker. Lipid modified peptide improves peptide pharmacokinetics. It prolongs the half-life in the circulation significantly. The most typical derivatization involves long-chain fatty acids. Fatty acid conjugated peptides can also be used for a number of different applications, e.g. for increasing their antibacterial activity or eukaryotic cell toxicity. | [Uses]
N'-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Alkyl-Chain | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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