ChemicalBook--->CAS DataBase List--->2358775-81-0

2358775-81-0

2358775-81-0 Structure

2358775-81-0 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2358775-81-0
[Synonyms]

[Molecular Formula]

C25H31FN4O4S2
[MOL File]

2358775-81-0.mol
[Molecular Weight]

534.67
Chemical PropertiesBack Directory
[Boiling point ]

823.6±65.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

10.20±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

VH 101, thiol (compound 20) is a VHL ligand for the synthesis of PROTACs[1].
[IC 50]

VHL
[storage]

Store at -20°C
[References]

[1] Miriam Girardini, et al. Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs. Bioorg Med Chem. 2019 Jun 15;27(12):2466-2479. DOI:10.1016/j.bmc.2019.02.048
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