| Identification | More | [Name]
2-Thiophenecarboxylic acid hydrazide | [CAS]
2361-27-5 | [Synonyms]
2-THIOPHENECARBOHYDRAZIDE 2-THIOPHENECARBOXYLIC ACID HYDRAZIDE 2-THIOPHENECARBOXYLIC HYDRAZIDE AKOS BBS-00004097 LABOTEST-BB LT00772322 THENOIC HYDRAZIDE THIOPHENE-2-CARBOHYDRAZIDE THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE THIOPHENE-2-CARBOXYLIC HYDRAZIDE 2-Thenoic hydrazide 2-Thenoylhydrazine 2-Thienylcarboxylic acid hydrazide 2-Thiophenecarbohydrazonic acid 2-Thiophenecarboxylic acid hyrazide Thiophene-2-carboxylic hydrazide, 98+% Thiophene-2-carbohydrazide 98% 2-Thiophenecarbonyl hydrazide 1-(2-Thienylcarbonyl)hydrazine | [EINECS(EC#)]
219-107-0 | [Molecular Formula]
C5H6N2OS | [MDL Number]
MFCD00005435 | [Molecular Weight]
142.18 | [MOL File]
2361-27-5.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29349990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
2-Thiophenecarboxylic acid hydrazide features a planar molecular structure with cis-oriented torsion angles of less than 10° and serves as a ligand for transition metal complexes involving manganese, cobalt, nickel, copper, zinc, cadmium, palladium, and ruthenium[1]. The compound reacts with isatin in ethanol under reflux to synthesize 2-thiophenecarbonylhydrazone-3-isatin[2]. | [Synthesis]
2-Thiophenecarboxylic acid hydrazide is synthesized from 2-thiophenecarboxylic acid derivatives via DCCI activation and subsequent hydrazinolysis, yielding the product at 87%[1]. | [References]
[1]Elshaarawy, R. F. M., & Janiak, C. (2011). 2-Thiophenecarbohydrazides: A Novel Efficient Method for the Synthesis of 2-Thiophenecarbohydrazide. Zeitschrift für Naturforschung B, 66(12), 1202–1208. https://doi.org/10.1515/znb-2011-1202 [2]Fahmi, M. R. G., Khumaidah, L., Ilmiah, T. K., Fadlan, A., & Santoso, M. (2018). 2-Thiophenecarboxylic acid hydrazide Derivatives: Synthesis and Anti-Tuberculosis Studies. IOP Conference Series: Materials Science and Engineering, 349, 012039. https://doi.org/10.1088/1757-899x/349/1/012039 |
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