ChemicalBook--->CAS DataBase List--->2361-27-5

2361-27-5

2361-27-5 Structure

2361-27-5 Structure
IdentificationMore
[Name]

2-Thiophenecarboxylic acid hydrazide
[CAS]

2361-27-5
[Synonyms]

2-THIOPHENECARBOHYDRAZIDE
2-THIOPHENECARBOXYLIC ACID HYDRAZIDE
2-THIOPHENECARBOXYLIC HYDRAZIDE
AKOS BBS-00004097
LABOTEST-BB LT00772322
THENOIC HYDRAZIDE
THIOPHENE-2-CARBOHYDRAZIDE
THIOPHENE-2-CARBOXYLIC ACID HYDRAZIDE
THIOPHENE-2-CARBOXYLIC HYDRAZIDE
2-Thenoic hydrazide
2-Thenoylhydrazine
2-Thienylcarboxylic acid hydrazide
2-Thiophenecarbohydrazonic acid
2-Thiophenecarboxylic acid hyrazide
Thiophene-2-carboxylic hydrazide, 98+%
Thiophene-2-carbohydrazide 98%
2-Thiophenecarbonyl hydrazide
1-(2-Thienylcarbonyl)hydrazine
[EINECS(EC#)]

219-107-0
[Molecular Formula]

C5H6N2OS
[MDL Number]

MFCD00005435
[Molecular Weight]

142.18
[MOL File]

2361-27-5.mol
Chemical PropertiesBack Directory
[Appearance]

white to light yellow crystal powder
[Melting point ]

136-139 °C(lit.)
[density ]

1.291 (estimate)
[refractive index ]

1.6430 (estimate)
[storage temp. ]

Store at RT.
[form ]

Crystalline Powder
[pka]

12.43±0.10(Predicted)
[color ]

Slightly yellow to beige
[BRN ]

114437
[InChI]

1S/C5H6N2OS/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8)
[InChIKey]

SOGBOGBTIKMGFS-UHFFFAOYSA-N
[SMILES]

NNC(=O)c1cccs1
[CAS DataBase Reference]

2361-27-5(CAS DataBase Reference)
[NIST Chemistry Reference]

2-Thiophenecarboxylic acid, hydrazide(2361-27-5)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HS Code ]

29349990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Methanol-->Hydrazinium hydroxide solution-->Ethyl 2-thiophenecarboxylate
[Preparation Products]

Perfluoropentanoic acid-->N-phenyl-2-(2-thienylcarbonyl)hydrazinecarbothioamide-->4-Amino-5-(2-thienyl)-4H-1,2,4-triazole-3-thiol-->4-Benzyl-5-(2-thienyl)-1,2,4-triazole-3-thiol
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2-Thiophenecarboxylic acid hydrazide(2361-27-5).msds
Hazard InformationBack Directory
[Chemical Properties]

white to light yellow crystal powder
[Uses]

2-Thiophenecarboxylic acid hydrazide features a planar molecular structure with cis-oriented torsion angles of less than 10° and serves as a ligand for transition metal complexes involving manganese, cobalt, nickel, copper, zinc, cadmium, palladium, and ruthenium[1]. The compound reacts with isatin in ethanol under reflux to synthesize 2-thiophenecarbonylhydrazone-3-isatin[2].
[Synthesis]

2-Thiophenecarboxylic acid hydrazide is synthesized from 2-thiophenecarboxylic acid derivatives via DCCI activation and subsequent hydrazinolysis, yielding the product at 87%[1].
[References]

[1]Elshaarawy, R. F. M., & Janiak, C. (2011). 2-Thiophenecarbohydrazides: A Novel Efficient Method for the Synthesis of 2-Thiophenecarbohydrazide. Zeitschrift für Naturforschung B, 66(12), 1202–1208. https://doi.org/10.1515/znb-2011-1202
[2]Fahmi, M. R. G., Khumaidah, L., Ilmiah, T. K., Fadlan, A., & Santoso, M. (2018). 2-Thiophenecarboxylic acid hydrazide Derivatives: Synthesis and Anti-Tuberculosis Studies. IOP Conference Series: Materials Science and Engineering, 349, 012039. https://doi.org/10.1088/1757-899x/349/1/012039
Spectrum DetailBack Directory
[Spectrum Detail]

2-Thiophenecarboxylic acid hydrazide(2361-27-5)MS
2-Thiophenecarboxylic acid hydrazide(2361-27-5)1HNMR
2-Thiophenecarboxylic acid hydrazide(2361-27-5)13CNMR
2-Thiophenecarboxylic acid hydrazide(2361-27-5)IR1
2-Thiophenecarboxylic acid hydrazide(2361-27-5)IR2
2-Thiophenecarboxylic acid hydrazide(2361-27-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

2-Thiophenecarboxylic acid hydrazide, 97%(2361-27-5)
[Alfa Aesar]

Thiophene-2-carboxylic hydrazide, 98+%(2361-27-5)
[Sigma Aldrich]

2361-27-5(sigmaaldrich)
[TCI AMERICA]

2-Thiophenecarboxylic Hydrazide,>95.0%(T)(2361-27-5)
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