| Identification | Back Directory | [Name]
L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- | [CAS]
2361119-87-9 | [Synonyms]
JYS003
VH032-C2-NH-Boc
L-Prolinamide, N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxobutyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
tert-Butyl (4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutyl)carbamate | [Molecular Formula]
C31H45N5O6S | [MOL File]
2361119-87-9.mol | [Molecular Weight]
615.78 |
| Hazard Information | Back Directory | [Uses]
VH032-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C2-NH-Boc will remove the protecting group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032-C2-NH-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands. |
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