| Identification | Back Directory | [Name]
Epitiostanol | [CAS]
2363-58-8 | [Synonyms]
10275S
Thiodrol
NSC 194684
Epitiostano
EPitostsanol
Epitiostanol
Epithiostanol
Epitiostanol RS
Epithioandrostanol
Epitiostanol USP/EP/BP
2α,3α-Epithio-5α-androstan-17β-ol
2,3-Epithio-1H-cyclopenta[a]phenanthrene
(2α,3α,5α,17β)-2,3-Epithioandrostan-17-ol
Androstan-17-ol,2,3-epithio-, (2a,3a,5a,17b)-
5α-Androstan-17β-ol, 2α,3α-epithio- (7CI, 8CI)
Androstan-17-ol, 2,3-epithio-, (2α,3α,5α,17β)-
2alpha,3alpha-Epithio-5alpha-androstan-17beta-ol
Epitiostanol (Contains up to 15% 3α,4α-Epithioandrostan Isomer)
2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstan-17-ol deriv. | [Molecular Formula]
C19H30OS | [MDL Number]
MFCD00866499 | [MOL File]
2363-58-8.mol | [Molecular Weight]
306.51 |
| Chemical Properties | Back Directory | [Melting point ]
127-128° | [alpha ]
D27.5 +24.4° (c = 1.054 in chloroform) | [Boiling point ]
417.1°C (rough estimate) | [density ]
1.0122 (rough estimate) | [refractive index ]
1.5700 (estimate) | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
15.10±0.60(Predicted) | [color ]
White to Off-White | [Water Solubility ]
1.2mg/L(37 ºC) |
| Hazard Information | Back Directory | [Originator]
Thiodrol,Shionogi,Japan,1977 | [Uses]
An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent. | [Definition]
ChEBI: Epitiostanol is an organic molecular entity. | [Manufacturing Process]
A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17-
acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in
diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while
stirring. To the reaction mixture, there is added water, and the separated
substance is collected by filtration and crystallized from hexane to give 2β,3β-
epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at
132.5°C to 134°C. | [Therapeutic Function]
Antineoplastic |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|