| Identification | More | [Name]
1,2-DIBROMO-4-FLUOROBENZENE | [CAS]
2369-37-1 | [Synonyms]
1,2-DIBROMO-4-FLUOROBENZENE
3,4-DIBROMOFLUOROBENZENE
1,2-Dibromo-4-fluorobenzene,98%
1,2-Dibromo-4-fluorobenzene 99%
1,2-Dibromo-4-fluorobenzene99% | [EINECS(EC#)]
219-131-1 | [Molecular Formula]
C6H3Br2F | [MDL Number]
MFCD00070780 | [Molecular Weight]
253.89 | [MOL File]
2369-37-1.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant | [HS Code ]
2903998090 |
| Hazard Information | Back Directory | [Reactivity Profile]
The Suzuki–Miyaura reaction of 1,2- dibromo-4-fluorobenzene with two equivalents of arylboronic acids 2a–d, i,v afforded the fluorinated terphenyls 15a–f in moderate to good yields. The best yields were obtained using 2.2 equivalents of the aryl boronic acid, Pd(PPh3)4 (0.03 equiv) as the catalyst, and Cs2CO3 (2.2 equiv) as the base (1,4-dioxane, 90 8C, 8 h). The low site-selectivity in the case of 1,2-dibromo-4-fluorobenzene (13) can be explained by the fact that the positions 1 and 2, located meta and para to the fluorine atom, are sterically and electronically very similar[1].
| [References]
[1] Muhammad Sharif . “Synthesis of functionalized fluorinated terphenyls by site-selective Suzuki–Miyaura cross-coupling reactions of dibrominated fluorobenzenes.” Journal of Fluorine Chemistry 146 (2013): Pages 19-36.
|
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|