| Identification | Back Directory | [Name]
4-((6-azidohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | [CAS]
2375555-72-7 | [Synonyms]
4-((6-azidohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | [Molecular Formula]
C19H22N6O4 | [MOL File]
2375555-72-7.mol | [Molecular Weight]
398.42 |
| Hazard Information | Back Directory | [Description]
HUN-55727 is a functionalized cereblon ligand for PROTAC? research and development. It incorporates an E3 ligase ligand plus an alkylC6 linker with terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has no formal name. | [Uses]
Pomalidomide 4'-alkylC6-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC6-azide can be connected to the ligand for protein by a linker to form PROTAC[1]. | [storage]
Store at -20°C | [References]
[1] Liu H, et al. Construction of an IMiD-based azide library as a kit for PROTAC research. Org Biomol Chem. 2021 Jan 6;19(1):166-170. DOI:10.1039/d0ob02120b |
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