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2376990-28-0

2376990-28-0 Structure

2376990-28-0 Structure
IdentificationBack Directory
[Name]

VH 032 phenol-linker 2
[CAS]

2376990-28-0
[Synonyms]

VH 032 phenol-linker 2
VH 032 phenol-alkylC6-amine
(S,R,S)-AHPC-phenol-alkylC6-amine (dihydrochloride)
[Molecular Formula]

C30H46ClN5O5S
[MDL Number]

MFCD32705124
[MOL File]

2376990-28-0.mol
[Molecular Weight]

624.24
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and an alkyl linker used for?PROTAC degrader[1].
[storage]

Store at -20°C
[References]

[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
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