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2378049-28-4

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2378049-28-4 Structure

2378049-28-4 Structure
IdentificationBack Directory
[Name]

HO-PEG7-CH2COOtBu
[CAS]

2378049-28-4
[Synonyms]

HO-PEG7-CH2COOtBu
Hydroxy-PEG7-CH2-Boc
Hydroxy-PEG7-CH2COOtBu
3,6,9,12,15,18,21-Heptaoxatricosanoic acid, 23-hydroxy-, 1,1-dimethylethyl ester
HO-PEG7-CH2COOtBu/3,6,9,12,15,18,21-Heptaoxatricosanoic acid, 23-hydroxy-, 1,1-dimethylethyl ester
[Molecular Formula]

C20H40O10
[MDL Number]

MFCD29917784
[MOL File]

2378049-28-4.mol
[Molecular Weight]

440.53
Chemical PropertiesBack Directory
[Boiling point ]

504.7±45.0 °C(Predicted)
[density ]

1.089±0.06 g/cm3(Predicted)
[pka]

14.36±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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