| Identification | Back Directory | [Name]
1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- | [CAS]
2414374-53-9 | [Synonyms]
1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- | [Molecular Formula]
C18H21N5O2 | [MOL File]
2414374-53-9.mol | [Molecular Weight]
339.39 |
| Hazard Information | Back Directory | [Description]
RET-IN-3 is a is a selective RETV804M kinase inhibitor. | [Uses]
RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM[1]. | [References]
[1] Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505. DOI:10.1021/acsmedchemlett.9b00615 |
|
|