| Identification | Back Directory | [Name]
1H-Imidazole-1-acetonitrile, 2-[[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]thio]- | [CAS]
2418577-51-0 | [Synonyms]
Cathepsin X-IN-1
1H-Imidazole-1-acetonitrile, 2-[[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]thio]- | [Molecular Formula]
C15H13N3O3S | [MOL File]
2418577-51-0.mol | [Molecular Weight]
315.35 |
| Chemical Properties | Back Directory | [Boiling point ]
587.4±60.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.51±0.31(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor with an IC50 of 7.13 μM. Cathepsin X-IN-1 decreases PC-3 cell migration with low cytotoxic[1]. | [References]
[1] Fonovi? UP, et al. Structure-activity relationships of triazole-benzodioxine inhibitors of cathepsin X. Eur J Med Chem. 2020 May 1;193:112218. DOI:10.1016/j.ejmech.2020.112218 |
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