| Identification | Back Directory | [Name]
Benzenesulfonamide, 5-[(1E)-2-(8-hydroxy-5-quinolinyl)diazenyl]-2-methyl- | [CAS]
2455508-17-3 | [Synonyms]
Glyoxalase I inhibitor 5
Benzenesulfonamide, 5-[(1E)-2-(8-hydroxy-5-quinolinyl)diazenyl]-2-methyl- | [Molecular Formula]
C16H14N4O3S | [MOL File]
2455508-17-3.mol | [Molecular Weight]
342.37 |
| Chemical Properties | Back Directory | [Boiling point ]
656.5±65.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.49±0.10(Predicted) | [color ]
Brown to orange |
| Hazard Information | Back Directory | [Uses]
Glyoxalase I inhibitor 5 (Compound 9h) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 1.28 μM. Glyoxalase I inhibitor 5 can be used as anticancer agent[1]. | [References]
[1] Al-Oudat BA, et al. Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents. Bioorg Med Chem. 2020 Aug 15;28(16):115608. DOI:10.1016/j.bmc.2020.115608 |
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