| Identification | Back Directory | [Name]
4-Benzoxazolecarboxylic acid, 2-[butyl[(1R)-1-[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]ethyl]amino]- | [CAS]
2465085-23-6 | [Synonyms]
ChemR23-IN-4
4-Benzoxazolecarboxylic acid, 2-[butyl[(1R)-1-[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]ethyl]amino]- | [Molecular Formula]
C27H26N6O3 | [MOL File]
2465085-23-6.mol | [Molecular Weight]
482.53 |
| Hazard Information | Back Directory | [Uses]
ChemR23-IN-4 (Compound 13) is a potent and orally efficacious ChemR23 inhibitor with an IC50 of 17 nM against human ChemR23[1]. | [References]
[1] Imaizumi T, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622. DOI:10.1016/j.bmc.2020.115622 |
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