| Identification | Back Directory | [Name]
4-Benzoxazolecarboxylic acid, 2-[(cyclopropylmethyl)[(1R)-1-[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-5'-methyl[1,1'-biphenyl]-4-yl]ethyl]amino]- | [CAS]
2465086-50-2 | [Synonyms]
ChemR23-IN-2
4-Benzoxazolecarboxylic acid, 2-[(cyclopropylmethyl)[(1R)-1-[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-5'-methyl[1,1'-biphenyl]-4-yl]ethyl]amino]- | [Molecular Formula]
C29H26N4O5 | [MOL File]
2465086-50-2.mol | [Molecular Weight]
510.54 |
| Hazard Information | Back Directory | [Uses]
ChemR23-IN-2 is a potent and orally efficacious ChemR23 inhibitor with an IC50 value of 3.2 nM. | [References]
[1] Imaizumi T, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622. DOI:10.1016/j.bmc.2020.115622 |
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