| Identification | Back Directory | [Name]
Urea, N-[5-cyano-4-[(S)-cyclopropylmethoxymethyl]-6-methyl-3-pyridinyl]-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)-3-pyridinyl]- | [CAS]
2504229-63-2 | [Synonyms]
MALT1-IN-3
Urea, N-[5-cyano-4-[(S)-cyclopropylmethoxymethyl]-6-methyl-3-pyridinyl]-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)-3-pyridinyl]- | [Molecular Formula]
C21H19F3N8O2 | [MOL File]
2504229-63-2.mol | [Molecular Weight]
472.43 |
| Hazard Information | Back Directory | [Uses]
MALT1-IN-3 (compound 122) is a potent MALT1 protease inhibitor, with an IC50 of 0.06 μM. MALT1-IN-3 has IC50 of 0.14 and 0.13 μM for human IL6/IL10 in OCI-LY3 cells, respectively[1]. | [References]
[1] Johannes Wilhelmus J Thuring, et al. Pyridine rings containing derivatives as malt1 inhibitors. WO2020208222A1 |
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