| Identification | Back Directory | [Name]
3-Pyridinecarboxamide, N-(3,6-dimethyl-9H-thioxanthen-9-yl)-1,2-dihydro-2-oxo-6-(trifluoromethyl)- | [CAS]
2576690-78-1 | [Synonyms]
HSD17B13-IN-9
3-Pyridinecarboxamide, N-(3,6-dimethyl-9H-thioxanthen-9-yl)-1,2-dihydro-2-oxo-6-(trifluoromethyl)- | [Molecular Formula]
C22H17F3N2O2S | [MOL File]
2576690-78-1.mol | [Molecular Weight]
430.44 |
| Chemical Properties | Back Directory | [Boiling point ]
619.7±55.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
6.23±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
HSD17B13-IN-9 (252) is a 17β-Hydroxysteroid dehydrogenases (HSD17B13) inhibitor, with an IC50 of 0.01 μM for 50 nM HSD17B13. Used in NAFLD (Nonalcoholic fatty liver diseases) research[1]. | [References]
[1] Joseph Vacca, et al. Modulators of hsd17b13 and methods of use thereof. Patent WO2021003295. |
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