| Identification | Back Directory | [Name]
1H-Indole-2-carboxamide, N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- | [CAS]
2582755-31-3 | [Synonyms]
MIF-IN-5
1H-Indole-2-carboxamide, N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- | [Molecular Formula]
C18H14FN5O2 | [MOL File]
2582755-31-3.mol | [Molecular Weight]
351.33 |
| Hazard Information | Back Directory | [Uses]
MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1]. | [References]
[1] Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849. DOI:10.1016/j.ejmech.2019.111849 |
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