| Identification | Back Directory | [Name]
2H-1,3-Oxazin-2-one, 3-(4-chloro-3-fluorophenyl)-4-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-ethoxycyclohexyl)-1H-benzimidazol-2-yl]tetrahydro-, (4S)- | [CAS]
2638507-71-6 | [Synonyms]
EP300/CBP-IN-1
2H-1,3-Oxazin-2-one, 3-(4-chloro-3-fluorophenyl)-4-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-ethoxycyclohexyl)-1H-benzimidazol-2-yl]tetrahydro-, (4S)- | [Molecular Formula]
C30H32ClFN4O4 | [MOL File]
2638507-71-6.mol | [Molecular Weight]
567.05 |
| Hazard Information | Back Directory | [Uses]
EP300/CBP-IN-1 (compound 172) is a potent EP300/CBP inhibitor with IC50s of 2.3 nM and 2.1 nM for CBP BRD and EP300 BRD, respectively. EP300/CBP-IN-1 has the inhibitory effect on the proliferation of prostate cancer CWR22RV1 cells[1]. | [References]
[1] Lei Fan, et al. An EP300/CBP inhibitor. CN112574189A. |
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