| Chemical Properties | Back Directory | [Boiling point ]
585.1±50.0 °C(Predicted) | [density ]
1.306±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
15.45±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
YAP-TEAD-IN-2 (compound 6) is a potent YAP-TEAD PPI (protein-protein interaction) inhibitor with IC50 is 2.7 nM[1]. | [References]
[1] Furet P, et al. The First Class of Small Molecules Potently Disrupting the YAP-TEAD Interaction by Direct Competition. ChemMedChem. 2022 Oct 6;17(19):e202200303. DOI:10.1002/cmdc.202200303 |
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