| Identification | Back Directory | [Name]
Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- | [CAS]
2734168-51-3 | [Synonyms]
HPK1-IN-12
Pyrazino[2,1-c][1,4]benzoxazine, 8-[5-(2-fluoro-6-methoxyphenyl)-1H-pyrazolo[4,3-b]pyridin-3-yl]-1,2,3,4,4a,5-hexahydro-3-methyl- | [Molecular Formula]
C25H24FN5O2 | [MOL File]
2734168-51-3.mol | [Molecular Weight]
445.49 |
| Hazard Information | Back Directory | [Uses]
HPK1-IN-12 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-12 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 85) [1]. | [References]
[1] Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1. |
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