| Chemical Properties | Back Directory | [Boiling point ]
724.9±60.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
14.26±0.20(Predicted) | [color ]
White to off-white | [InChIKey]
GYWOVBUGFWWSJR-UHFFFAOYSA-N | [SMILES]
O=C1CN(C2C=C(F)C(CN3CCC(C)(C)CC3)=CC=2F)CC2(CCN(C3=NC=NC(NC)=C3)CC2)N1 |
| Hazard Information | Back Directory | [Uses]
UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM. | [Biological Activity]
UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM. | [References]
[1]. Dolbois A, et al. 1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors. J Med Chem. 2021 Sep 9;64(17):12738-12760. |
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