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2764880-87-5

2764880-87-5 Structure

2764880-87-5 Structure
IdentificationBack Directory
[Name]

3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-
[CAS]

2764880-87-5
[Synonyms]

3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-
[Molecular Formula]

C23H21N5OS
[MOL File]

2764880-87-5.mol
[Molecular Weight]

415.51
Chemical PropertiesBack Directory
[Boiling point ]

675.2±55.0 °C(Predicted)
[density ]

1.367±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 2mg/mL, clear (Warmed)
[form ]

Solid
[pka]

11.38±0.40(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

BAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor.
[Uses]

BAY-179 is a potent, selective, and species cross-reactive complex I inhibitor. BAY-179 shows IC50 values of 79 nM, 38 nM, 27 nM, and 47 nM for human, mouse, rat, and dog complex I, respectively[1].
[References]

[1] Mowat J, et al. Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179. ACS Med Chem Lett. 2022;13(3):348-357. Published 2022 Feb 18. DOI:10.1021/acsmedchemlett.1c00666
Spectrum DetailBack Directory
[Spectrum Detail]

3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-(2764880-87-5)1HNMR
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