| Identification | Back Directory | [Name]
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- | [CAS]
2764880-87-5 | [Synonyms]
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- | [Molecular Formula]
C23H21N5OS | [MOL File]
2764880-87-5.mol | [Molecular Weight]
415.51 |
| Chemical Properties | Back Directory | [Boiling point ]
675.2±55.0 °C(Predicted) | [density ]
1.367±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear (Warmed) | [form ]
Solid | [pka]
11.38±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
BAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor. | [Uses]
BAY-179 is a potent, selective, and species cross-reactive complex I inhibitor. BAY-179 shows IC50 values of 79 nM, 38 nM, 27 nM, and 47 nM for human, mouse, rat, and dog complex I, respectively[1]. | [References]
[1] Mowat J, et al. Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179. ACS Med Chem Lett. 2022;13(3):348-357. Published 2022 Feb 18. DOI:10.1021/acsmedchemlett.1c00666 |
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Merck KGaA
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