| Identification | Back Directory | [Name]
Butanoic acid, 2-[[3-cyano-2-(2′-fluoro-3′-methyl[1,1′-biphenyl]-4-yl)-1,7-naphthyridin-4-yl]amino]-, (2R)- | [CAS]
2922280-34-8 | [Synonyms]
Butanoic acid, 2-[[3-cyano-2-(2′-fluoro-3′-methyl[1,1′-biphenyl]-4-yl)-1,7-naphthyridin-4-yl]amino]-, (2R)- | [Molecular Formula]
C26H21FN4O2 | [MOL File]
2922280-34-8.mol | [Molecular Weight]
440.47 |
| Chemical Properties | Back Directory | [Boiling point ]
732.6±60.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
3.69±0.30(Predicted) | [color ]
Light yellow to light brown |
| Hazard Information | Back Directory | [Uses]
BAY-091 is a novel potent and highly selective inhibitor of the kinase PIP4K2A. | [References]
[1] Wortmann L, et al. Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A. J Med Chem. 2021 Nov 11;64(21):15883-15911. DOI:10.1021/acs.jmedchem.1c01245 |
|
|