| Identification | Back Directory | [Name]
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- | [CAS]
2799717-96-5 | [Synonyms]
c-Myc inhibitor 9
Imidazo[2,1-b]benzothiazole-7-carboxamide, 2-[4-(1-aminocyclopropyl)phenyl]-N-[3-(1-piperidinyl)propyl]- | [Molecular Formula]
C27H31N5OS | [MOL File]
2799717-96-5.mol | [Molecular Weight]
473.63 |
| Hazard Information | Back Directory | [Uses]
c-Myc inhibitor 9 (compound 332) is a c-Myc inhibitor with an logEC50 of ≥6. c-Myc inhibitor 9 inhibits tumor growth in nude mouse models. c-Myc inhibitor 9 can be used for cancer research[1]. | [in vivo]
c-Myc inhibitor 9 (3 mg/kg; i.p., twice a week for 49 days) effectively inhibits tumor growth in nude mice with A549 xenografts[1]. | Animal Model: | NMRI female nude mice with A549 xenografts[1] | | Dosage: | 3 mg/kg | | Administration: | Intraperitoneal injection; 3 mg/kg, twice a week, for 49 days | | Result: | Reduced tumor volume.
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| [References]
[1] Sheppard, David William, et al. Preparation of heteroaryl compounds as c-MYC mRNA translation modulators and uses thereof in the treatment of cancer. WO2022150316. 2022. |
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