| Identification | Back Directory | [Name]
5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(bicyclo[6.1.0]non-4-yn-9-ylmethyl) 17-(2,3,4,5,6-pentafluorophenyl) ester | [CAS]
2904607-26-5 | [Synonyms]
| [Molecular Formula]
C28H34F5NO8 | [MOL File]
2904607-26-5.mol | [Molecular Weight]
607.56 |
| Chemical Properties | Back Directory | [Boiling point ]
650.9±55.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Oil | [pka]
12.05±0.46(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG4-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|