| Identification | Back Directory | [Name]
PROPARACAINE | [CAS]
298-50-0 | [Synonyms]
PROPARACAINE
propantheline
Propanthelinium
PROPARACAINE USP/EP/BP
Proparacaine
Propantheline
Diisopropylmethyl[2-(9H-xanthene-9-ylcarbonyloxy)ethyl]aminium
diisopropyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]ammonium
[2-[(9H-Xanthen-9-ylcarbonyl)oxy]ethyl]diisopropylmethylaminium
methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
methyl-di(propan-2-yl)-[2-(9H-xanthen-9-ylcarbonyloxy)ethyl]azanium
(2-hydroxyethyl)diisopropylmethyl-ammoniuxanthene-9-carboxylate(ester)
2-propanaminium,n-methyl-n-(1-methylethyl)-n-(2-((9h-xanthen-9-ylcarbonyl)oxy)
N-Methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-2-propanaminium
2-Propanaminium,N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]- | [EINECS(EC#)]
206-063-2 | [Molecular Formula]
C16H26N2O3 | [MDL Number]
MFCD00864455 | [MOL File]
298-50-0.mol | [Molecular Weight]
294.39 |
| Hazard Information | Back Directory | [Uses]
Anticholinergic. | [Uses]
Propantheline is used for treating stomach ulcers. | [Definition]
ChEBI: Propantheline is a member of xanthenes. | [Brand name]
Pro-Banthine (Searle). | [Pharmacology]
The pharmacological action of propantheline is qualitatively similar to atropine. It has a
weaker effect on the CNS than atropine. Unlike atropine, it exhibits greater ganglioblocking action than antimuscarinic action. Moreover, upon overdose it causes neuromuscular
curare-like blockage. | [Synthesis]
Propanetheline, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-
ylcarbonyl) oxy]ethyl]-2-propanaminium bromide (14.1.11), is synthesized by reacting xanthen-9-carboxylic acid chloride with 2-di-iso-propylaminoethanol, giving the ester (14.1.10),
which upon reaction with methylbromide turns into the quaternary salt, propantheline
(14.1.11) [12,13].
| [Veterinary Drugs and Treatments]
Proparacaine is a rapid acting topical anesthetic useful for a variety
of ophthalmic procedures including tonometry (intraocular pressure
measurement), relief of corneal pain to facilitate examination,
biopsy/sample collection, and to distinguish between corneal and
uveal pain. Proparacaine primarily anesthetizes the cornea; with
limited penetration into conjunctiva. Anesthesia is of short duration
(5 – 10 minutes). |
|
| Company Name: |
AFINE CHEMICALS LIMITED
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| Telephone: |
+86-571-85134551 +86-18958018566 |
| Website: |
www.afinechem.com/index.html |
| Company Name: |
PT CHEM GROUP LIMITED
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| Telephone: |
+86-85511178; +86-85511178 |
| Website: |
https://www.chemicalbook.com/manufacturer/henan-lihao-chem-plant-25020/ |
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