| Identification | More | [Name]
5-Aminofluorescein | [CAS]
3326-34-9 | [Synonyms]
1-AMINOFLUORESCEIN
1-FLUORESCEINAMINE
4-AMINOFLUORESCEIN
4-AMINOFLUORESCEIN ISOMER I
5-amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
5-AMINO-3',6'-DIHYDROXYSPIRO[ISOBENZOFURAN-1(3H),9'-(9H)XANTHEN]-3-ONE
5-AMINOFLUORESCEIN
5-AMINOFLUORESCEIN ISOMER I
AMINOFLUORESCEIN
FLUORESCEINAMINE
FLUORESCEINAMINE, ISOMER 1
FLUORESCEINAMINE ISOMER I
9’-[9h]xanthen]-3-one,5-amino-3’,6’-dihydroxy-spiro[isobenzofuran-1(3h
Fluoresceinamine，isomerⅡ
5-AMINOFLUORESCEIN, FOR FLUORESCENCE
FLUORESCEIN AMINE ISOMER I 99%
4-AMINOFLUORESCEIN (ISOMER 1)
Fluoresceinamine isomer I, pure
FLUORESCENAMINEISOMERI
6-Amino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one | [EINECS(EC#)]
222-043-6 | [Molecular Formula]
C20H13NO5 | [MDL Number]
MFCD00005052 | [Molecular Weight]
347.32 | [MOL File]
3326-34-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Dark Red Solid | [Melting point ]
223 °C (dec.)(lit.) | [Boiling point ]
481.89°C (rough estimate) | [density ]
1.3724 (rough estimate) | [refractive index ]
1.5180 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
DMF: 5 mg/ml; DMSO: 5 mg/ml | [form ]
powder
| [pka]
9.34±0.20(Predicted) | [color ]
red-brown
| [Water Solubility ]
Soluble in water (partly), methanol (10 mg/ml), and acetone. | [Usage]
Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens | [λmax]
496 nm | [BRN ]
48395 | [Stability:]
Light and Moisture Sensitive | [Major Application]
diagnostic assay manufacturing
hematology
histology | [InChI]
1S/C20H13NO5/c21-10-1-4-14-13(7-10)19(24)26-20(14)15-5-2-11(22)8-17(15)25-18-9-12(23)3-6-16(18)20/h1-9,22-23H,21H2 | [InChIKey]
GZAJOEGTZDUSKS-UHFFFAOYSA-N | [SMILES]
Nc1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35 | [CAS DataBase Reference]
3326-34-9(CAS DataBase Reference) | [EPA Substance Registry System]
3326-34-9(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10 | [TSCA ]
Yes | [HS Code ]
32049090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Description]
5-AMF is a fluorescent probe for carboxylic acids and glutamine, and it also can be coupled to aldehydes and ketones. | [Chemical Properties]
Dark Red Solid | [Uses]
5-aminofluorescein is also used to prepare FITC Isomer I (CDX-F0011, CDX-F0020). It is a chemical used as molecular probe and important as fluorescent dye and for derivatives. Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens. | [Uses]
Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens | [Uses]
Glycosaminoglycuronans react with 5-aminofluorescein to yield fluorescent derivatives. 5-aminofluorescein is also used to prepare FITC Isomer I (F-011, F-020). | [Definition]
ChEBI: A primary amino compound that is fluorescein carrying an amino substituent at C-5. Building block/intermediate for the synthesis of the fluorescent dye flourescein; also used to produce N-(fluorescein-5-yl)maleamic acid. | [Preparation]
The preparation of 5-aminofluorescein is carried out either by first saponification of 5-nitrofluorescein acetates with alcohol alkali, followed by reduction of the obtained 5-nitrofluorescein in a solution of alcohol alkali with hydrazine hydrate on a nickel catalyst to obtain 5-aminofluorescein , Or by boiling in an aqueous solution of sodium sulfide. The restoration of the nitro group and the saponification of acetates in the second case occurs in one stage.
| [General Description]
Fluoresceinamine, isomer I belongs to the class of derivatized fluoresceins. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|