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6-Aminofluorescein

6-Aminofluorescein Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
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6-Aminofluorescein manufacturers

  • 6-Aminofluorescein
  • 6-Aminofluorescein pictures
  • $1.00
  • 2026-03-20
  • CAS:51649-83-3
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • 6-Aminofluorescein
  • 6-Aminofluorescein pictures
  • 2025-06-27
  • CAS:51649-83-3
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 500000kg
6-Aminofluorescein Basic information
Product Name:6-Aminofluorescein
Synonyms:(4Z)-4-(dimethylaminomethylidene)-5-methyl-2-phenyl-3-pyrazolone;6-amino-3',6'-dihydroxyspiro[isobenzofuran-1(3h),9'-[9h]xanthene]-3-one;AMINOFLUORESCEIN ISOMER II;5-AMINOFLUORESCEIN (ISOMER II);FLUORESCEINAMINE, ISOMER 2;FLUORESCEINAMINE, ISOMER II;6-AMINOFLUORESCEIN, FOR FLUORESCENCE;FLUORESCEINMINE, ISOMER 2,
CAS:51649-83-3
MF:C20H13NO5
MW:347.32
EINECS:257-334-7
Product Categories:marker;Fluorescent Labels and Indicators;Fluorescent Labels & Indicators
Mol File:51649-83-3.mol
6-Aminofluorescein Structure
6-Aminofluorescein Chemical Properties
Melting point 285 °C (dec.)(lit.)
Boiling point 481.89°C (rough estimate)
density 1.3724 (rough estimate)
refractive index 1.5180 (estimate)
storage temp. 2-8°C
solubility methanol: soluble1mg/mL, clear, yellow to very dark yellow-orange
pka9.34±0.20(Predicted)
form Solid
color Yellow to Orange
λmax495 nm
BRN 51708
Stability:Light and Moisture Sensitive
InChIInChI=1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2
InChIKeyYOAWSYSKQHLFPM-UHFFFAOYSA-N
SMILESC12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC(N)=C1)C(=O)O2
CAS DataBase Reference51649-83-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
10-23
HS Code 29329990
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
6-Aminofluorescein Usage And Synthesis
Description6-Aminofluorescein (6-AF) is a new fluorescence dye with bright colors and high fluorescence intensity. Its chemical structure history contains a nitrogen group and a fluorescent group. The presence of the fluorescent component enables 6-Aminofluorescein to emit a distinct fluorescent signal when excited, making it valuable for fluorescent labeling and imaging. It is widely used in biological science research, chemical analysis and fluorescence microscopy.
Chemical PropertiesYellow Solid
UsesFluorescent labeling reagent for proteins. Glycosaminoglycuronans react with 6-aminofluorescein to yield fluorescent derivatives. Used in the fluorescent antibody technique for rapid identification of pathogens.
Biological Functions6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed "buckysomes". 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein. 6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).
References[1] BHARATE G Y, QIN H, FANG J. Poly(Styrene-Co-Maleic Acid)-Conjugated 6-Aminofluorescein and Rhodamine Micelle as Macromolecular Fluorescent Probes for Micro-Tumors Detection and Imaging[J]. Journal of Personalized Medicine, 2022, 12. DOI:10.3390/jpm12101650.
[2] Müller, Werner EG, and Heinz Christoph Schrder, eds. Biological Response Modifiers—Interferons, Double-Stranded RNA and 2′, 5′-Oligoadenylates. Vol. 14. Springer Science & Business Media, 2012.
6-Aminofluorescein Preparation Products And Raw materials
Raw materials5-Nitrofluorescein-->3',6'-Bis(acetyloxy)-6-nitrospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one-->4-Nitrophthalic acid-->Resorcinol
Preparation Products5-Aminofluorescein
Tag:6-Aminofluorescein(51649-83-3) Related Product Information
6-Aminocaproic acid Fluorescein Fluorescein isothiocyanate Fluorescein Sodium EC 1.14.14.3 3-Aminophenol Fluorescein diacetate Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride Fluorescein 6-isothiocyanate 5-Aminofluorescein 5-Nitrofluorescein AMINOFLUORESCEIN,1-AMINOFLUORESCEIN,5(6)-Aminofluorescein,5-AMINOFLUORESCEIN ISOMER I,4-AMINOFLUORESCEIN,4-AMINOFLUORESCEIN ISOMER I 5-(OCTADECANOYLAMINO)FLUORESCEIN 4,5-DIAMINOFLUORESCEIN DIACETATE ZNAF-2 DA Erythrosin B isothiocyanate, isomer II