| Identification | More | [Name]
Furan-2-carbohydrazide | [CAS]
3326-71-4 | [Synonyms]
2-FURANCARBOHYDRAZIDE
2-FUROHYDRAZIDE
2-FUROIC ACID HYDRAZIDE
2-FUROIC HYDRAZIDE
AKOS BBS-00004105
FURAN-2-CARBOHYDRAZIDE
FURAN-2-CARBOXYLIC ACID HYDRAZIDE
FURANE-2-CARBOXYLIC ACID HYDRAZIDE
SPECS AN-068/40170015
2-furancarbohydrazonicacid
2-furancarbonylhydrazide
2-furancarboxylicacid,hydrazide
2-furoylhydrazide
2-furylcarbonylhydrazide
2-furylcarboxylicacidhydrazide
pyromucicacidhydrazide
Furan-2-CarboxylicHydrazide
2-Furoic acid hydrazide, 98+%
2-Furoic acid hydrazide, 2-Furoylhydrazine
1-(2-Furanylcarbonyl)hydrazine | [EINECS(EC#)]
222-046-2 | [Molecular Formula]
C5H6N2O2 | [MDL Number]
MFCD00003235 | [Molecular Weight]
126.11 | [MOL File]
3326-71-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Beige crystals | [Melting point ]
77-79 °C (lit.) | [Boiling point ]
279°C(lit.) | [density ]
1.3541 (rough estimate) | [refractive index ]
1.5090 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
soluble in Methanol | [form ]
Crystals | [pka]
12.18±0.10(Predicted) | [color ]
Beige | [BRN ]
114435 | [InChI]
InChI=1S/C5H6N2O2/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8) | [InChIKey]
SKTSVWWOAIAIKI-UHFFFAOYSA-N | [SMILES]
O1C=CC=C1C(NN)=O | [CAS DataBase Reference]
3326-71-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
LV1925000
| [HS Code ]
29321900 |
| Hazard Information | Back Directory | [Chemical Properties]
Beige crystals | [Uses]
2-Furoic hydrazide (2-Furoylhydrazine) was used to study the Fourier transform infrared spectra, 1H NMR and 13C NMR spectra. It was also used as a reagent for determination of carbohydrates. | [Synthesis]
General procedure for the synthesis of 2-furancarbohydrazide from furan-2-carboxamide and 4-methyl-3-penten-2-one hydrazone: 111.1 g of furan-2-carboxamide was placed in a four-necked flask fitted with a stirrer, a dropping funnel, a thermometer, and a distillation column, and 224 g of acetone acridine was added. Stirring was turned on and the reaction mixture was heated to 100 to 120 °C to ensure complete dissolution of furan-2-carboxamide in acetone acridazine. Subsequently, 70 ml of water was slowly added through a dropping funnel to maintain the reaction temperature between 100 °C and 120 °C. The ammonia produced during the reaction was exported through a distillation column and the ammonia was recovered by condensation at 54°C to 58°C. The condensed water vapor was returned to the reaction flask to continue participating in the reaction. After the water droplet addition was completed, heating of the reaction mixture was continued. The progress of the reaction was monitored by analyzing the amount of furan-2-carboxamide in the reaction solution. Once the furan-2-carboxamide was fully reacted, the flask was distilled with acetone and water fully connected under nitrogen protection. The residual solid in the flask was recrystallized with ethanol and dried to give 119.6 g of 2-furancarboxamide. | [References]
[1] Patent: CN106967020, 2017, A. Location in patent: Paragraph 0010 |
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