| Identification | Back Directory | [Name]
AC-NLE-PRO-NLE-ASP-AMC | [CAS]
355140-49-7 | [Synonyms]
AC-NLE-PRO-NLE-ASP-AMC
AC-NLE-PRO-NLE-ASP-MCA
N-Acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine
L-α-Asparagine, N-acetyl-L-norleucyl-L-prolyl-L-norleucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | [Molecular Formula]
C33H45N5O9 | [MDL Number]
MFCD02259625 | [MOL File]
355140-49-7.mol | [Molecular Weight]
655.74 |
| Chemical Properties | Back Directory | [Boiling point ]
1028.3±65.0 °C(Predicted) | [density ]
1.278±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C
| [form ]
Solid | [pka]
4.10±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis[1][2][3]. | [References]
[1] Dunlop RA, et al. The impact of specific oxidized amino acids on protein turnover in J774 cells. Biochem J. 2008 Feb 15;410(1):131-40. DOI:10.1042/BJ20070161
[2] Kirk-Ballard H, et al. An extract of Artemisia dracunculus L. inhibits ubiquitin-proteasome activity and preserves skeletal muscle mass in a murine model of diabetes. PLoS One. 2013;8(2):e57112. DOI:10.1371/journal.pone.0057112
[3] Pakavathkumar P, et al. Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. Sci Rep. 2015 Sep 24;5:13730. DOI:10.1038/srep13730 |
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| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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