| Identification | Back Directory | [Name]
Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]- | [CAS]
364052-84-6 | [Synonyms]
ZINC04177596
Benzamide, 4-[2-[1,5-dihydro-1-(4-nitrophenyl)-5-oxo-3-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]- | [Molecular Formula]
C22H16N6O4 | [MOL File]
364052-84-6.mol | [Molecular Weight]
428.4 |
| Hazard Information | Back Directory | [Description]
ZINC04177596 is a novel Nef Protein Inhibitor; Anti-HIV. | [Uses]
ZINC04177596 is a potent HIV-negative factor (HIV-Nef) protein inhibitor. Nef is an accessory gene product of HIV and has an imperative role in viral replication and AIDS pathogenesis[1]. | [References]
[1] Moonsamy S, et al. Identification of Binding Mode and Prospective Structural Features of Novel Nef Protein Inhibitors as Potential Anti-HIV Drugs. Cell Biochem Biophys. 2017;75(1):49-64. DOI:10.1007/s12013-016-0774-1 |
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