ChemicalBook--->CAS DataBase List--->3767-28-0

3767-28-0

3767-28-0 Structure

3767-28-0 Structure
IdentificationMore
[Name]

4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
[CAS]

3767-28-0
[Synonyms]

4'-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
P-NITROPHENYL A-D-GLUCOPYRANOSIDE
P-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE
P-NITROPHENYL-ALPHA-D-GLUCOSIDE
PNP-ALPHA-D-GLC
PNP ALPHA-D-GLUCOPYRANOSIDE
PNP-ALPHA-GLU
4-nitrophenylalpha-glucoside
4-Nitrophenyl α-D-glucopyranoside
P-Nitrophenyl-Alpha-D-GlucopyranosideA.R.
.alpha.-D-Glucopyranoside, 4-nitrophenyl
4-nitrophenyl-à-d-glucopyranoside
4-Nitrophenyla-D-glucopyranoside
4-Nitrophenyl α-D-Glucoside
p-Nitrophenol α-D-Glucoside
4-Nitrophenyl-ɑ-D-glucopyranoside, 98+%
4-Nitrophenyl alpha-D-Glucopyranoside [Substrate for alpha-D-Glucosidase]
4-Nitrophenyl a-D-Glucoside
p-Nitrophenol a-D-Glucoside
[EINECS(EC#)]

223-189-3
[Molecular Formula]

C12H15NO8
[MDL Number]

MFCD00064088
[Molecular Weight]

301.25
[MOL File]

3767-28-0.mol
Chemical PropertiesBack Directory
[Appearance]

White Crystals
[Melting point ]

210-216 °C
[Boiling point ]

442.39°C (rough estimate)
[density ]

1.3709 (rough estimate)
[refractive index ]

218.5 ° (C=0.5, H2O)
[storage temp. ]

2-8°C
[solubility ]

DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 0.3 mg/ml
[form ]

Crystalline Powder
[pka]

12.55±0.70(Predicted)
[color ]

Off-white to light yellow
[Water Solubility ]

Soluble in water, warm ethanol and methanol.
[Usage]

Substrate for a-glucosidase inhibitor
[Detection Methods]

HPLC
[BRN ]

92212
[InChI]

InChI=1/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/s3
[InChIKey]

IFBHRQDFSNCLOZ-ZIQFBCGOSA-N
[SMILES]

O(C1C=CC(N(=O)=O)=CC=1)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |&1:10,12,15,17,19,r|
[CAS DataBase Reference]

3767-28-0(CAS DataBase Reference)
[Storage Precautions]

Light sensitive;Store under nitrogen
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362+P364-P403+P233-P501c
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[F ]

3-10-21
[HS Code ]

29389090
[Storage Class]

11 - Combustible Solids
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Sodium hydroxide-->Methanol-->Sodium-->Phosphorus oxitrichloride-->Acetic anhydride-->Sodium acetate-->Zinc chloride-->D(+)-Glucose-->Butyl acetate-->4-Nitrophenol-->Benzenesulfonic acid, ethenyl-, polymer with diethenylbenzene-->(4-Nitro)phenyl-2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranoside-->Glucose pentaacetate-->Sucrose
[Preparation Products]

4-Nitrophenyl-beta-D-glucopyranoside
Hazard InformationBack Directory
[Chemical Properties]

White Crystals
[Uses]

Substrate for a-glucosidase inhibitor
[Uses]

Substrate for α-glucosidase inhibitor.
[Definition]

ChEBI: An alpha-D-glucoside that is beta-D-glucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.
[Biological Activity]

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavagethe substrate is converted to a yellow-colored product.
[Purification Methods]

Purify 4-nitrophenyl--D-glucopyranoside by recrystallisation from H2O, MeOH or EtOH. [Jermyn Aust J Chem 7 202 1954, Montgomery et al. J Am Chem Soc 64 690 1942.] It is a chromogenic substrate from -glucosidases [Oliviera et al. Anal Biochem 1 1 3 1881981], and is a C5227substrate for glucansucrases [Binder & Robyt Carbohydr Research 124 2871983]. [Beilstein 17/7 V 53.]
Spectrum DetailBack Directory
[Spectrum Detail]

4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE(3767-28-0)1HNMR
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE(3767-28-0)13CNMR
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE(3767-28-0)IR
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE(3767-28-0)FT-IR
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE(3767-28-0)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-Nitrophenyl-alpha-D-glucopyranoside, 99%(3767-28-0)
[Alfa Aesar]

4-Nitrophenyl-alpha-D-glucopyranoside, 98+%(3767-28-0)
[Sigma Aldrich]

3767-28-0(sigmaaldrich)
[TCI AMERICA]

4-Nitrophenyl alpha-D-Glucopyranoside  [Substrate for alpha-D-Glucosidase](3767-28-0)
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