| Identification | Back Directory | [Name]
Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide | [CAS]
423731-64-0 | [Synonyms]
CTX-0124143
Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide | [Molecular Formula]
C17H13FN2O3S | [MOL File]
423731-64-0.mol | [Molecular Weight]
344.36 |
| Hazard Information | Back Directory | [Description]
CTX-012414 is a KAT6A inhibitor with IC50 value of 0.49 μM and KD value of 0.38 -M. | [Uses]
CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton[1]. | [References]
[1] Duan Y, et al. Discovery of N-(2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy. Eur J Med Chem. 2023 Nov 15;260:115770. DOI:10.1016/j.ejmech.2023.115770 |
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