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452072-27-4

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452072-27-4 Structure

452072-27-4 Structure
IdentificationBack Directory
[Name]

2,5-Dioxo-1-(4-(pyridin-2-yldisulfanyl)pentanoyloxy)pyrrolidine-3-sulfonic acid
[CAS]

452072-27-4
[Synonyms]

Sulfo-SPP
2,5-Dioxo-1-(4-(pyridin-2-yldisulfanyl)pentanoyloxy)pyrrolidine-3-sulfonic acid
[Molecular Formula]

C14H16N2O7S3
[MDL Number]

MFCD20230500
[MOL File]

452072-27-4.mol
[Molecular Weight]

420.48
Chemical PropertiesBack Directory
[density ]

1.61±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

-0.04±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
[IC 50]

Disulfide Cleavable Linker; Cleavable Linker
[References]

[1] Ravi V. J. Chari, et al. Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents. US6441163B1.
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