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452782-06-8

452782-06-8 Structure

452782-06-8 Structure
IdentificationBack Directory
[Name]

D-Phenylalaninamide, N-acetyl-D-α-aspartyl-D-tryptophyl-D-phenylalanyl-D-lysyl-D-alanyl-D-phenylalanyl-D-tyrosyl-D-α-aspartyl-D-lysyl-D-valyl-D-alanyl-D-α-glutamyl-D-lysyl-D-phenylalanyl-D-lysyl-D-α-glutamyl-D-alanyl-
[CAS]

452782-06-8
[Synonyms]

D-Phenylalaninamide, N-acetyl-D-α-aspartyl-D-tryptophyl-D-phenylalanyl-D-lysyl-D-alanyl-D-phenylalanyl-D-tyrosyl-D-α-aspartyl-D-lysyl-D-valyl-D-alanyl-D-α-glutamyl-D-lysyl-D-phenylalanyl-D-lysyl-D-α-glutamyl-D-alanyl-
[Molecular Formula]

C114H156N24O28
[MOL File]

452782-06-8.mol
[Molecular Weight]

2310.6
Chemical PropertiesBack Directory
[Boiling point ]

2350.4±65.0 °C(Predicted)
[density ]

1.308±0.06 g/cm3(Predicted)
[pka]

4.19±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases[1].
[References]

[1] Bloedon LT, et al., Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients. J Lipid Res. 2008 Jun;49(6):1344-52. DOI:10.1194/jlr.P800003-JLR200
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