| Identification | Back Directory | [Name]
OT antagonist 1 | [CAS]
479080-38-1 | [Synonyms]
OT antagonist 1
3-Pyrrolidinone, 1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-5-(3-methyl-1,2,4-oxadiazol-5-yl)-, 3-(O-methyloxime), (5S)- | [Molecular Formula]
C22H22N4O3 | [MDL Number]
MFCD31692342 | [MOL File]
479080-38-1.mol | [Molecular Weight]
390.44 |
| Chemical Properties | Back Directory | [Boiling point ]
592.6±60.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
-0.26±0.39(Predicted) |
| Hazard Information | Back Directory | [Uses]
OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM. | [References]
[1] Brown A, et al. Design and optimization of potent, selective antagonists of Oxytocin. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4278-81. DOI:10.1016/j.bmcl.2008.06.098 |
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