| Identification | Back Directory | [Name]
(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione | [CAS]
496791-37-8 | [Synonyms]
AR C15585
AR-C 155858
AR-C 155858;AR C15585
AR-C155858;AR C155858
inhibit,AR-C155858,Inhibitor,Monocarboxylate Transporter,AR-C-155858,ARC155858,AR C155858
(S)-6-((3,5-dimethyl-1H-pyrazol-4-yl)methyl)-5-(4-hydroxyisoxazolidine-2-carbonyl)-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-
4-Isoxazolidinol, 2-[[6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,2,3,4-tetrahydro-3-methyl- 1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidin-5-yl]carbonyl]-, (4S)- | [Molecular Formula]
C21H27N5O5S | [MDL Number]
MFCD22124476 | [MOL File]
496791-37-8.mol | [Molecular Weight]
461.53 |
| Chemical Properties | Back Directory | [Melting point ]
198-202∶C | [Boiling point ]
763.1±70.0 °C(Predicted) | [density ]
1.395 | [storage temp. ]
Store at -20°C | [solubility ]
insoluble in H2O; ≥52.5 mg/mL in DMSO; ≥57.8 mg/mL in EtOH | [form ]
solid | [pka]
13.53±0.20(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Uses]
AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. | [Biological Activity]
Cell permeable: yes''Primary Target
MCT1 | [IC 50]
MCT1; MCT2 | [storage]
Store at -20°C |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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