| Identification | Back Directory | [Name]
7-METHYLGUANINE | [CAS]
578-76-7 | [Synonyms]
Epiguanin
NSC 19647
NSC 193444
EPIGUANINE
7-methyl-guanin
7-METHYLGUANINE
N7-Methylguanine
7-METHYLGUANINE 98+%
7-METHYLGUANINE USP/EP/BP
2-Amino-7-methylhypoxanthine
2-Amino-7-methyl-7H-purin-6-ol
7-Methylguanine >=98.0% (HPLC)
2-amino-7-methyl-3H-purin-6-one
2-azanyl-7-methyl-3H-purin-6-one
2-AMINO-6-HYDROXY-7-METHYLPURINE
2-AMino-7-Methyl-1H-purin-6(7H)-one
2-amino-1,7-dihydro-7-methyl-6h-purin-6-on
2-amino-1,7-dihydro-7-methyl-6h-purin-6-one
2-Amino-7-methyl-1,7-dihydro-6H-purin-6-one
6H-Purin-6-one, 2-amino-1,7-dihydro-7-methyl-
2-Amino-6-hydroxy-7-methylpurine, Epiguanine
2-amino-7-methyl-1,7-dihydro-6H-purin-6-one578-76-7 | [EINECS(EC#)]
209-431-0 | [Molecular Formula]
C6H7N5O | [MDL Number]
MFCD00038003 | [MOL File]
578-76-7.mol | [Molecular Weight]
165.15 |
| Chemical Properties | Back Directory | [Melting point ]
370°C | [Boiling point ]
292.98°C (rough estimate) | [density ]
1.3629 (rough estimate) | [refractive index ]
1.8500 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Aqueous Base (Slightly) | [form ]
Solid | [pka]
9.78±0.20(Predicted) | [color ]
Light Brown to Brown | [BRN ]
174245 | [InChI]
1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12) | [InChIKey]
FZWGECJQACGGTI-UHFFFAOYSA-N | [SMILES]
Cn1cnc2N=C(N)NC(=O)c12 |
| Hazard Information | Back Directory | [Uses]
Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer. | [Definition]
ChEBI: A 7-methylguanine that is 1,7-dihydro-6H-purin-6-one substituted by an amino group at position 2 and a methyl group at position 7. | [IC 50]
Human Endogenous Metabolite | [Purification Methods]
Crystallise it from water. UV: at 280nm (pH 2.1). The picrate has m 267o (270-272o dec, also reported). [Beilstein 26 H |
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