| Identification | More | [Name]
4-Bromobenzoyl chloride | [CAS]
586-75-4 | [Synonyms]
4-BROMOBENZOYL CHLORIDE
AKOS BBS-00003926
P-BROMOBENZOYL CHLORIDE
4-Brombenzoesαurechlorid
4-bromo-benzoylchlorid
Benzoyl chloride, p-bromo-
Benzoylchloride,4-bromo-
Benzoylchloride,p-bromo-
p-Bromobenzoyl chloride, p-bromo-
4-Brorobenzoylchloride
4-Bromobenzoyl chloride, 98+%
4-Bromo-1-benzenecarbonyl chloride
4-Bromobenzoic acid chloride | [EINECS(EC#)]
209-580-1 | [Molecular Formula]
C7H4BrClO | [MDL Number]
MFCD00000683 | [Molecular Weight]
219.46 | [MOL File]
586-75-4.mol |
| Chemical Properties | Back Directory | [Appearance]
White to light brown low melting solid | [Melting point ]
36-39 °C(lit.) | [Boiling point ]
246 °C | [density ]
1.6111 (rough estimate) | [refractive index ]
1.5963 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
Chloroform, Methanol (Slightly) | [form ]
Low Melting Solid | [color ]
White to light brown | [Water Solubility ]
Soluble in methanol. Reacts with water forming Hcl. | [Sensitive ]
Moisture Sensitive | [BRN ]
636641 | [Stability:]
Moisture Sensitive | [InChI]
1S/C7H4BrClO/c8-6-3-1-5(2-4-6)7(9)10/h1-4H | [InChIKey]
DENKGPBHLYFNGK-UHFFFAOYSA-N | [SMILES]
ClC(=O)c1ccc(Br)cc1 | [CAS DataBase Reference]
586-75-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzoyl chloride, 4-bromo-(586-75-4) | [Storage Precautions]
Store under inert gas | [EPA Substance Registry System]
586-75-4(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P260-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R37:Irritating to the respiratory system. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [F ]
19-21 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29163900 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
White to light brown low melting solid | [Uses]
4-Bromobenzoyl chloride is used in the synthesis of HIV-1 protease inhibitors. It is also used in the synthesis of oxazoles, cyclohexanone derivatives as analgesic and antimicrobial agents. | [Purification Methods]
Check IR of a film to see if OH bands are present. If absent then recrystallise from pet ether and dry it in vacuo. If OH bands are weak, then distil it in vacuo and recrystallise if necessary. If OH bands are very strong, then treat with an equal volume of redistilled SOCl2 reflux for 2hours, then evaporate excess of SOCl2 and distil the residual oil or low melting solid. Store it in the dark away from moisture. LACHRYMATORY. [Martin & Partington J Chem Soc 1175 1936, Beilstein 9 IV 1023.] |
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China Langchem Inc.
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