| Identification | More | [Name]
Ethanesulfonyl chloride | [CAS]
594-44-5 | [Synonyms]
ETHANESULFONYL CHLORIDE
ETHANESULPHONYL CHLORIDE
ETHYLSULFONYL CHLORIDE
1-Ethanesulfonyl chloride
1-ethanesulfonylchloride
Ethane sulfochloride
Ethylsulfochloride
ethylsulfurylchloride
TL 77
tl77
ETHANESULFONYL CHLORIDE, 99+%
Ethanesulfonyl chloride, 98+%
1,2-Ethane-disulfonic
Ethane-1-sulfonic acid chloride
Ethanesulfonic acid chloride
Ethyl sulfone chloride | [EINECS(EC#)]
209-842-5 | [Molecular Formula]
C2H5ClO2S | [MDL Number]
MFCD00007460 | [Molecular Weight]
128.58 | [MOL File]
594-44-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear light brownish to pinkish-purple liquid | [Melting point ]
-70°C | [Boiling point ]
177 °C (lit.) | [density ]
1.357 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.452(lit.)
| [Fp ]
182 °F
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
soluble in dichloromethane,Ether | [form ]
Liquid | [color ]
Clear colorless to light yellow or light brownish to pinkish-purple | [Water Solubility ]
DECOMPOSES | [Sensitive ]
Moisture Sensitive | [BRN ]
773865 | [InChIKey]
FRYHCSODNHYDPU-UHFFFAOYSA-N | [CAS DataBase Reference]
594-44-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethanesulfonyl chloride(594-44-5) | [EPA Substance Registry System]
594-44-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R21/22:Harmful in contact with skin and if swallowed .
R23:Toxic by inhalation.
R34:Causes burns.
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2927 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
KI8050000
| [F ]
19-21 | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29049090 | [Hazardous Substances Data]
594-44-5(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Chemical Properties]
clear light brownish to pinkish-purple liquid | [Uses]
Chloroethylsulfone was used in discovery of a selective inhibitor of oncogenic B-raf kinase with potent antimelanoma activity. | [Application]
Ethanesulfonyl chloride can make sulfonyl-substituted imides, methide lithium salts, and pentafluoroethanesulfonyl fluoride, a fluorinated surfactant. It is an intermediate in synthesizing new, low-cost, non-fluorinated, sulfonyl-substituted imide and methide lithium salts and an intermediate in preparing the fluorinated surfactant pentafluoroethanesulfonyl fluoride.
| [Synthesis Reference(s)]
Journal of the American Chemical Society, 61, p. 2548, 1939 DOI: 10.1021/ja01878a085 |
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